Search results for "Intergenic region"

showing 10 items of 49 documents

A genetic study on subtropical Anadenanthera colubrina (Vell.) Brenan var. cebil (Griseb.) Altschul tree from Northwestern Argentina

2017

Anadenanthera colubrina (Vell.) Brenan var. cebil (Griseb.) Altschul is a tree species in South America important for its cultural, economic, and medicinal uses. In addition, it represents a trace in memory of the forests that have decreased over the years and for this reason it is not only interesting to study but also important to preserve the tree species for future generations. In this paper, we have characterized the genetic diversity of four populations. We collected seeds from four different sites: San Bernardo (B), El Cebilar (C), Metán (M), and El Gallinato (G) in Salta Province, North Argentina. We then compared the intergenic transcribed sequences of ribosomal DNA, a known geneti…

0106 biological sciences0301 basic medicineGenetic diversitybiologyconservationColubrinaForestrySubtropicsBiodiversitybotanybiology.organism_classificationBiodiversity; botany; deforestation; conservation; phylogenetic010603 evolutionary biology01 natural sciencesGenetic analysis03 medical and health sciencesTree (descriptive set theory)030104 developmental biologyIntergenic regionBotanySettore BIO/03 - Botanica Ambientale E ApplicatadeforestationphylogeneticAnadenanthera colubrinaRibosomal DNA
researchProduct

The chloroplast genome of the lichen‐symbiont microalga Trebouxia sp. Tr9 (Trebouxiophyceae, Chlorophyta) shows short inverted repeats with a single …

2019

The Trebouxiophyceae is the class of Chlorophyta algae from which the highest number of chloroplast genome (cpDNA) sequences has been obtained. Several species in this class participate in symbioses with fungi to form lichens. However, no cpDNA has been obtained from any Trebouxia lichen-symbiont microalgae, which are present in approximately half of all lichens. Here, we report the sequence of the completely assembled cpDNA from Trebouxia sp. TR9 and a comparative study with other Trebouxio-phyceae. The organization of the chloroplast genome of Trebouxia sp. TR9 has certain features that are unusual in the Trebouxiophyceae and other green algae. The most remarkable characteristics are the …

0106 biological sciencesGeneticsTrebouxiaNuclear genebiology010604 marine biology & hydrobiologyTrebouxiophyceaePlant ScienceAquatic Sciencebiology.organism_classification010603 evolutionary biology01 natural sciencesGenomeIntergenic regionChloroplast DNARRNA OperonViridiplantaeJournal of Phycology
researchProduct

Plastid DNA Homogeneity in Celtis australis L. (Cannabaceae) and Nerium oleander L. (Apocynaceae) throughout the Mediterranean Basin

2015

International audience; Premise of research. Riparian plants are highly dependent on water sources; consequently, general climatic conditions are less important to these taxa relative to woodland and shrubland species. This leads to interesting research questions regarding riparian plant taxa. Research on phylogeography of Mediterranean riparian tree and shrub species is scarce. In this article, we investigated the plastidial genetic diversity in Celtis australis L. (hackberry) and Nerium oleander L. (oleander) throughout the Mediterranean Basin. Both species are distributed in gullies, rivers, and stream banks under warm temperate climates. Methodology. Eighteen cpSSR loci and three noncod…

0106 biological sciencesMediterranean climateved/biology.organism_classification_rank.speciesPlant ScienceBiology[SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomy010603 evolutionary biology01 natural sciencesShrubMediterranean BasinShrubland03 medical and health sciencesIntergenic region[SDV.EE.ECO]Life Sciences [q-bio]/Ecology environment/EcosystemsBotanyTemperate climateEcology Evolution Behavior and Systematics030304 developmental biologyRiparian zoneCeltis australis0303 health sciencesgeographygeography.geographical_feature_categoryEcologyved/biology15. Life on land[SDV.BV.BOT]Life Sciences [q-bio]/Vegetal Biology/Botanicsbiology.organism_classification[SDE.BE]Environmental Sciences/Biodiversity and Ecology
researchProduct

Genome reduction of the aphid endosymbiont Buchnera aphidicola in a recent evolutionary time scale.

2007

International audience; Genome reduction, a typical feature of symbiotic bacteria, was analyzed in the last stages of evolution of Buchnera aphidicola, the primary aphid endosymbiont, in two neutrally evolving regions: the pseudogene cmk and an intergenic region. These two regions were examined in endosymbionts from several lineages of their aphid host Rhopalosiphum padi, and different species of the same genus, whose divergence times ranged from 0.62 to 19.51 million years. Estimates of nucleotide substitution rates were between 4.3 and 6.7 x 10(-9) substitution/site/year, with G or C nucleotides being substituted around four times more frequently than A or T. Two different types of indel …

0106 biological sciencesTime FactorsPseudogeneBiology010603 evolutionary biology01 natural sciencesGenomeDNA MitochondrialEvolution Molecular03 medical and health sciencesIntergenic regionBuchneraPhylogeneticsGeneticsAnimalsMolecular clockIndelSymbiosisPhylogeny030304 developmental biologyGenetics0303 health sciences[SDV.GEN]Life Sciences [q-bio]/GeneticsBase SequenceGeographyNucleotidesGeneral Medicinebiology.organism_classificationFixation (population genetics)HaplotypesAphidsCalibrationMutationBuchneraGenome BacterialGene
researchProduct

A Methodology to Study Pseudogenized lincRNAs

2021

Long intergenic noncoding RNAs (lincRNAs) are known to be tissue specifically expressed and able to regulate functional protein-coding genes: some can even act as competing endogenous RNAs (ceRNAs), because microRNAs can bind to them instead of the corresponding mRNA binding sites. Some lincRNAs contain remnants of protein-coding sequences and it has been hypothesized that they might arise after a pseudogenization processes. However, a major limitation in the study of such phenomenon is the lack of proper computational tools designed to align/analyze protein-coding sequences and noncoding sequences. To overcome this limitation, we published a method that finds the remnants of protein-coding…

0301 basic medicineCompeting endogenous RNAPseudogeneSequence alignmentComputational biologyBiology03 medical and health sciences030104 developmental biology0302 clinical medicineIntergenic regionmicroRNASingle pointGene030217 neurology & neurosurgerySequence (medicine)
researchProduct

First phenotypic and genotypic description of Fasciola hepatica infecting highland cattle in the state of Mexico, Mexico

2018

Abstract Fascioliasis is a plantborne and zoonotic parasitic disease caused by fasciolid liver flukes. Fasciola hepatica is the only fasciolid species described in the Americas. Human fascioliasis endemic areas are mainly located in high altitude areas of the Americas. Given the necessity to characterize F. hepatica populations involved, the phenotypic and genotypic features of fasciolid adults infecting cattle in the highland area of Toluca, State of Mexico, Mexico, were analyzed and compared to fasciolid materials from the Northern Bolivian Altiplano, representing the altiplanic transmission pattern in a hyperendemic scenario. A computer image analysis system (CIAS) was applied on the bas…

0301 basic medicineMicrobiology (medical)FascioliasisGenotypeRange (biology)030231 tropical medicinebiology.animal_breedPopulationCattle DiseasesZoologyDNA RibosomalMicrobiology03 medical and health sciences0302 clinical medicineIntergenic regionHepaticaparasitic diseasesGeneticsAnimalsFasciola hepaticaGeography MedicaleducationMexicoMolecular BiologyRibosomal DNAEcology Evolution Behavior and SystematicsBase Compositioneducation.field_of_studybiologyHighland CattleFasciola hepatica030108 mycology & parasitologyLiver flukebiology.organism_classificationPhenotypeInfectious DiseasesHaplotypesCattleSequence AnalysisInfection, Genetics and Evolution
researchProduct

Dynamic evolution of mitochondrial genomes in Trebouxiophyceae, including the first completely assembled mtDNA from a lichen-symbiont microalga (Treb…

2019

AbstractTrebouxiophyceae (Chlorophyta) is a species-rich class of green algae with a remarkable morphological and ecological diversity. Currently, there are a few completely sequenced mitochondrial genomes (mtDNA) from diverse Trebouxiophyceae but none from lichen symbionts. Here, we report the mitochondrial genome sequence of Trebouxia sp. TR9 as the first complete mtDNA sequence available for a lichen-symbiont microalga. A comparative study of the mitochondrial genome of Trebouxia sp. TR9 with other chlorophytes showed important organizational changes, even between closely related taxa. The most remarkable change is the enlargement of the genome in certain Trebouxiophyceae, which is princ…

0301 basic medicinePrasiolalesTrebouxiaMitochondrial DNALichensEvolutionlcsh:MedicineBiologyDNA MitochondrialGenomeArticleEvolution MolecularOpen Reading Frames03 medical and health sciences0302 clinical medicineIntergenic regionSpecies SpecificityChlorophytaPhylogeneticsMicroalgaelcsh:SciencePhylogenyMultidisciplinaryTrebouxiophyceaelcsh:RSequence Analysis DNAGroup II intronbiology.organism_classificationIntrons030104 developmental biologyTandem Repeat SequencesEvolutionary biologyGenome Mitochondriallcsh:QPlant sciences030217 neurology & neurosurgeryScientific Reports
researchProduct

A Clonal Lineage of Fusarium oxysporum Circulates in the Tap Water of Different French Hospitals.

2016

ABSTRACT Fusarium oxysporum is typically a soilborne fungus but can also be found in aquatic environments. In hospitals, water distribution systems may be reservoirs for the fungi responsible for nosocomial infections. F. oxysporum was previously detected in the water distribution systems of five French hospitals. Sixty-eight isolates from water representative of all hospital units that were previously sampled and characterized by translation elongation factor 1α sequence typing were subjected to microsatellite analysis and full-length ribosomal intergenic spacer (IGS) sequence typing. All but three isolates shared common microsatellite loci and a common two-locus sequence type (ST). This S…

0301 basic medicineSystemVeterinary medicineLineage (genetic)Sequence analysis030106 microbiologyBiologyInfectionsApplied Microbiology and BiotechnologyMicrobiology03 medical and health sciencesIntergenic regionOriginPeptide Elongation Factor 1FusariumPhylogeneticsFusarium oxysporum[SDV.IDA]Life Sciences [q-bio]/Food engineeringHumansTypingDrinking-waterDNA FungalPhylogenyVegetative compatibility groupsDiversityEcologyPublic and Environmental Health MicrobiologyDrinking Water[ SDV.IDA ] Life Sciences [q-bio]/Food engineeringFungiAustraliafood and beveragesSequence Analysis DNARibosomal RNAbiology.organism_classificationHospitals030104 developmental biologyFusariosisMicrosatelliteDNA IntergenicFranceFood ScienceBiotechnologyMicrosatellite RepeatsApplied and environmental microbiology
researchProduct

Identification of transcribed protein coding sequence remnants within lincRNAs

2018

Abstract Long intergenic non-coding RNAs (lincRNAs) are non-coding transcripts >200 nucleotides long that do not overlap protein-coding sequences. Importantly, such elements are known to be tissue-specifically expressed and to play a widespread role in gene regulation across thousands of genomic loci. However, very little is known of the mechanisms for the evolutionary biogenesis of these RNA elements, especially given their poor conservation across species. It has been proposed that lincRNAs might arise from pseudogenes. To test this systematically, we developed a novel method that searches for remnants of protein-coding sequences within lincRNA transcripts; the hypothesis is that we can t…

0301 basic medicineTransposable elementSequence analysisPseudogeneRetrotransposonComputational biologyBiologyOpen Reading Frames03 medical and health sciences0302 clinical medicineIntergenic regionSequence Analysis ProteinGeneticsHumansAmino Acid SequenceGeneRegulation of gene expressionBase SequenceSequence Analysis RNAComputational Biology030104 developmental biologyGene Expression RegulationDNA IntergenicRNA Long NoncodingSequence AlignmentAlgorithms030217 neurology & neurosurgeryBiogenesisNucleic Acids Research
researchProduct

Epimutation at human chromosome 14q32.2 in a boy with a upd(14)mat-like clinical phenotype.

2009

Recently, three reports described deletions and epimutations affecting the imprinted region at chromosome 14q32.2 in individuals with a phenotype typical for maternal uniparental disomy of chromosome 14 [upd(14)mat]. In this study, we describe another patient with upd(14)mat-like phenotype including low birth weight, neonatal feeding problems, muscular hypotonia, motor and developmental delay, small hands and feet, and truncal obesity. Conventional cytogenetic analyses, fluorescence in situ hybridization subtelomere screening, multiplex ligation-dependent probe amplification analysis of common microdeletion and microduplication syndromes, and methylation analysis of SNRPN all gave normal re…

AdultMalecongenital hereditary and neonatal diseases and abnormalitiesMolecular Sequence DataMothersBiologyMethylationPolymorphism Single NucleotideEpigenesis GeneticGenomic ImprintingIntergenic regionGeneticsmedicineHumansAbnormalities MultipleEpigeneticsChildGenetics (clinical)GeneticsChromosomes Human Pair 14Muscular hypotoniamedicine.diagnostic_testBase SequenceChromosomeUniparental DisomySubtelomerePhenotypeDifferentially methylated regionsPhenotypeMutationFemaleFluorescence in situ hybridizationClinical genetics
researchProduct